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Li Shuangjie, Ph.D., is an associate professor in the basic medical college of Henan University, a young member of the Committee of Translational Medicine of China Microcirculation Society, and a member of the Committee of Tumor Markers of China Anti-cancer Association.

2021 / 07-So far, Henan University, Basic Medical College, Associate Professor

2016 / 09-2021 / 07, Yangzhou University, School of Veterinary Medicine, PhD

2013 / 09-2016 / 07, Nanjing Agricultural University, School of Veterinary Medicine, Master 's Degree

2009 / 09-2013 / 07, Henan Agricultural University, College of Animal Husbandry and Medical Engineering, Bachelor of Science

ATL3 promotes the progression of low-grade glioma through ISG15-mediated ubiquitination modification.

The mechanism of natural immune receptor RIG-I promoting the malignant progression of glioma and its targeted small molecule drug screening.

（1）Shao Q,Li S, Cao Q, Gu H, Zhang J, Zhang Y, Zhang K, Zheng W, Chen N, Shang S, Zhu J. Development of Specific Monoclonal Antibodies against Porcine RIG-I-like Receptors Revealed the Species Specificity. Int J Mol Sci. 2023 Feb 18;24(4):4118.

（2）Li S, Yang J, Zhu Y, Wang H, Ji X, Luo J, Shao Q, Xu Y, Liu X, Zheng W, Meurens F, Chen N, Zhu J. Analysis of Porcine RIG-I Like Receptors Revealed the Positive Regulation of RIG-I and MDA5 by LGP2. Front Immunol. 2021 May 18;12:609543.

（3）Li S, Shao Q, Zhu Y, Ji X, Luo J, Xu Y, Liu X, Zheng W, Chen N, Meurens F, Zhu J. Porcine RIG-I and MDA5 Signaling CARD Domains Exert Similar Antiviral Function Against Different Viruses. Front Microbiol. 2021 Jun 11;12:677634.

（4）Li S, Yang J, Zhu Y, Ji X, Wang K, Jiang S, Luo J, Wang H, Zheng W, Chen N, Ye J, Meurens F, Zhu J. Chicken DNA Sensing cGAS-STING Signal Pathway Mediates Broad Spectrum Antiviral Functions. Vaccines (Basel). 2020 Jul 9;8(3):369.

（5）Ao D,Li S, Jiang S, Luo J, Chen N, Meurens F, Zhu J. Inter-relation analysis of signaling adaptors of porcine innate immune pathways. Mol Immunol. 2020 May;121:20-27.

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